Zenrelia™ success stories
Meet some of the dogs whose itching was successfully managed and reduced by Zenrelia.
Over half a million dogs treated with Zenrelia worldwide since launch1
Up to 12 months' experience for dogs in Brazil, US, Japan and Canada - a testament to Zenrelia's efficacy and safety
SUCCESS STORY: MAZE
Maze is a middle-aged neutered Staffordshire Bull Terrier. The owner reported that Maze has pruritus year-round and previous treatment with Apoquel®, OTC hydrocortisone and antihistamines were ineffective. The owner's goal was to provide treatment that would manage Maze’s symptoms by providing year-round relief.
BEFORE
Maze presented with severe pruritus, epidermal collarettes, alopecia and erythema. He was diagnosed with suspected canine atopic dermatitis.
The treatment plan included:
- Zenrelia: start once-daily dosing to control pruritus
- Start: appropriate antibiotic and medicated shampoos/creams
AFTER
- 11 days after beginning treatment, Maze’s pruritus had significantly decreased
- Complete resolution of lesions on abdomen and axillae; lichenification much improved
“Incredible resolution of pruritus based on the PVAS score alone.”
Brooke West, veterinary surgeon
Next steps were to:
- Continue to use Zenrelia as the primary prescription to control Maze’s pruritus
- Finish course of antibiotics and continue using medicated shampoos/creams as needed
SUCCESS STORY: KAREN
Karen is a senior spayed Toy Poodle. The owner noted that Karen was not only extremely itchy, but that she had been more irritable than usual. Although there was no significant dermatitis, the symptoms Karen experienced were still affecting her quality of life. The owner's goal was to provide treatment that would control Karen's pruritus and improve her quality of life.
BEFORE
- Karen presented with severe pruritus with clear ocular discharge. Significant saliva staining on paws, forelimbs and mouth
- The treatment plan was to start once daily dosing of Zenrelia to control pruritus
AFTER
- Notable decrease in degree of pruritus
- Less irritable both at home and at the recheck examination
“Karen is no longer itching and is in a much better mood!”
Chessie Green, veterinary surgeon
Next steps were to continue to use Zenrelia as the primary prescription to control Karen’s pruritus.
SUCCESS STORY: CODA
Coda is a middle-aged intact male French Bulldog. The owner reported that Coda presented with chronic allergies with no improvement when treated with Apoquel, Cytopoint®, and limited relief with ongoing allergen specific immunotherapy (ASIT) and a prescription diet. Coda responded well to cyclosporine but developed gastrointestinal issues. The owner's goal was to provide effective and long-lasting treatment that Coda could tolerate.
BEFORE
Coda presented with pruritus, excoriations, sores, alopecia, erythema, epidermal collarettes and lichenification.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
- Start: topical antibiotic while waiting for results of culture to prescribe systemic antibiotics
- Continue: ASIT and prescription diet
AFTER
- Significant improvement in the degree of pruritus and no adverse effects observed
- Visible hair regrowth on the dorsal head
“Coda’s owner was very happy with his improvement, and the lesions and pruritus had almost completely resolved [at this recheck].”
Curtis Plowgian, veterinary dermatologist
Next steps were to:
- Zenrelia: continue to use as primary prescription to control Coda’s pruritus
- Other treatments: continue ASIT and prescription diet
SUCCESS STORY: BRIDGETTE
Bridgette is a senior spayed Chihuahua. The owner reported that Bridgette had undergone a variety of treatments since 2018 with little success in managing her symptoms. She had minimal response to Cytopoint and Apoquel, and experienced negative side effects with antibiotics and steroids. The owner's goal was to provide treatment that would manage Bridgette’s symptoms without side effects.
BEFORE
Bridgette presented with chronic, severe pruritus with excoriations, alopecia, and widespread erythema.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
- Other treatment: alternative antibiotic
AFTER
- Substantial overall improvement in the degree of redness and inflammation, and owner reported that Bridgette was comfortable enough to sleep through the night again
- No adverse side effects like Bridgette had experienced with some other treatments
“The best and quickest response to all treatments Bridgette has ever received for her atopic dermatitis.”
Tonya Campbell, veterinary surgeon
Next steps were to:
- Continue to use Zenrelia as the primary prescription to control Bridgette's pruritus
SUCCESS STORY: MOWGLI
Mowgli is a senior neutered Staffordshire Bull Terrier. The owner reported that Mowgli had incomplete control of seasonal allergic skin disease with Cytopoint injections every 4 weeks. The owner's goal was to provide treatment that would improve Mowgli’s comfort level during seasonal flare-ups.
BEFORE
Mowgli presented with severe pruritus with excoriations, erythema and lichenification.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
- Continue Cytopoint
- Add medicated shampoos/creams
AFTER
- Significant improvement in pruritus, erythema and lichenification in the affected flank area and axillae
“Malassezia dermatitis and pruritus improved as well.”
Brooke West, veterinary surgeon
Next steps were to:
- Zenrelia: continue to use as primary prescription treatment to control pruritus
- Other treatments: continue use of Cytopoint plus medicated shampoos/creams as need
SUCCESS STORY: LOVE
Love is a senior spayed mixed breed. The owner reported that Love remained very itchy while undergoing ASIT and using medicated shampoos/creams. Previous treatment with Apoquel and Cytopoint provided only limited relief. The owner's goal was to find treatment to aid in the management of Love’s symptoms while undergoing ASIT.
BEFORE
Love presented with chronic pruritus, alopecia, erythema, pustules, hyperpigmentation, and lichenification.
The treatment plan included:
- Zenrelia: start once-daily dosing to control pruritus
- Continue: ASIT, medicated shampoos/creams, appropriate antibiotics and antifungals to treat pyoderma and Malassezia dermatitis
AFTER
- Noticeable decrease in the degree of inflammation and pruritus
- Interdigital erythema resolved
“The Zenrelia seemed to make a big difference as the itchiness really declined after 48 hours of taking it.”
Klaus Loft, veterinary dermatologist
Next steps were to:
- Zenrelia: continue to use as an adjunct to ASIT
- Other treatments: continue using medicated shampoos/creams as needed, and finish course of antibiotics and antifungal
SUCCESS STORY: MARSHALL
Marshall is a 14-year-old neutered Australian Cattle Dog mix. The owner reported that Marshall had incomplete control of chronic, non-seasonal allergic dermatitis with use of Apoquel, Cytopoint and a limited ingredient diet. The owner's goal was to have treatment that would provide immediate relief.
BEFORE
Marshall presented with severe pruritus with periocular and distal limb alopecia.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
- Address skin infections with appropriate antibiotics and antifungals
- Continue limited ingredient diet
AFTER
- Notable improvement of periocular alopecia and hair regrowth on distal limbs
- Greatly decreased pruritus
- Resolution of pruritus in 27 days of treatment with Zenrelia
- Increased energy levels noted
“Marshall’s owner reported that his symptoms had never improved this significantly with prior treatments.”
Matthew Lane, veterinary surgeon
Next steps were to:
- Zenrelia: continue to use as primary therapy to control Marshall’s allergic dermatitis symptoms
- Other treatments: continue limited ingredient diet
SUCCESS STORY: BUDDY
Buddy is a senior neutered mixed breed. The owner reported that Buddy had incomplete control of atopy and food allergy dermatitis while on a hypoallergenic diet, oral steroids, antihistamines, Cytopoint, an off-label dose of Apoquel, and medicated shampoos/creams. The owner's goal was to find a treatment that would allow Buddy to decrease the number of treatments needed to manage his symptoms.
BEFORE
Buddy presented with chronic pruritus, excoriations, erythema, alopecia, hyperpigmentation and lichenification.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
- Other treatment: Continue antihistamines and hypoallergenic diet
AFTER
- Since starting Zenrelia, Buddy has been less pruritic and more playful at home
“Last time I saw [Buddy], he was not clinically very different than today, but he was on far more medication and has [now] maintained at that ‘good’ level with much less medication.”
Karly Robinson, veterinary dermatologist
Next steps were to:
- Zenrelia: continue to use as primary prescription to control Buddy’s pruritus
- Other treatments: decrease/discontinue antihistamine use, continue using medicated shampoos/creams on paws as needed, start appropriate otitis medication
SUCCESS STORY: FRANK
Frank is a middle-aged neutered French Bulldog. The owner reported that Frank’s symptoms were being managed with oral corticosteroids and a prescription diet, but there was concern about long-term corticosteroid use. Previous treatment with Apoquel and Cytopoint had been unsuccessful. The owner's goal was to find a nonsteroidal treatment to manage Frank’s pruritus.
BEFORE
Frank presented with pruritus, urticaria and alopecia.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus.
- Continue: prescription diet and appropriate medications to manage pre-existing GI symptoms (chronic vomiting and diarrhoea).
AFTER
- Canine atopic dermatitis symptoms significantly improved
“Zenrelia [allows] us to maintain the skin and pruritus without steroids.”
Curtis Plowgian, veterinary dermatologist
Next steps were to:
- Zenrelia: continue to use as primary prescription to control Frank’s pruritus
- Other treatments: continue feeding prescription diet and using appropriate medications to manage pre-existing GI symptoms. Start steroid inhaler to manage allergic bronchitis, now Frank is no longer on oral steroids for skin condition
SUCCESS STORY: HUDSON
Hudson is a middle-aged neutered Labrador Retriever. The owner reported that Hudson's previous treatment with Apoquel and steroids was ineffective, and Hudson is experiencing insufficient relief and flares on Cytopoint, antihistamines, skin supplements and food for sensitive skin and GI issues. The owner's goal was to find an effective treatment that provides sufficient relief from Hudson’s symptoms of canine atopic dermatitis.
BEFORE
Hudson presented with pruritus, hyperpigmentation, periocular alopecia and clear ocular discharge.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
AFTER
- Significant improvement in the degree of pruritus
- Increased comfort and energy levels
- No adverse effects observed
“[Hudson’s] owner noted that [Hudson] was feeling a lot better at home and had even slept solidly [since starting Zenrelia].”
Miranda Anthony, veterinary surgeon
Next steps were to:
- Zenrelia: continue to use as primary prescription to control Hudson’s pruritus
SUCCESS STORY: MOLLY
Molly is a senior spayed Shih Tzu. The owner reported that Molly was taking Apoquel at the time of her initial visit but was still severely pruritic. She had previously been treated with combined antihistamine & corticosteroid treatment. The owner's goal was to find a treatment that effectively manages Molly’s pruritus.
BEFORE
Molly presented with pruritus, erythema, epidermal collarettes and lichenification.
The treatment plan included:
- Zenrelia: start once daily dosing to control pruritus
- Other treatment: start anti fungal treatment
AFTER
- Complete resolution of pruritus and skin lesions by day 19 of treatment with Zenrelia
“Molly is a great candidate for Zenrelia as a primary control of her dermatitis!”
Tonya Campbell, veterinary surgeon
Next steps were to:
- Zenrelia: continue to use as primary prescription to control Molly’s pruritus
Questions?
Zenrelia Resources
ASIT, allergen specific immunotherapy; PVAS, pruritus visual analogue scale.
- Elanco global sales data, June 2025.
