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Pet owners please visit our website MyPet&I.

AVIPRO SALMONELLA DUO

The only live dual-strain vaccine containing S.Enteritidis and S.Typhimurium.

Providing superior, direct protection1 against both regulated Salmonella strains in layers2


Protect your flock, your profits, and human health: An exclusive education series on AviPro Salmonella Duo 

This infographic series explores the critical role of Salmonella control in ensuring food safety and maximising poultry production. Discover the product benefits of AviPro Salmonella Duo, learn how it safeguards your operation against Salmonella challenges, and ultimately contributes to food safety and human health. 

Co-Fermentation Infographic

Learn more about AviPro Salmonella Duo's unique co-fermentation process.

Egg Claim Infographic

Learn more about how only AviPro Salmonella Duo protects against internal contamination from S. Enteritidis. 

Differentiation Testing Infographic

Learn more about why differentiation testing with AviPro Salmonella Duo is not necessary.

Optimal Salmonella protection is a priority

Salmonella is costly (a Salmonella outbreak among free-range birds in the UK can cost producers up to £17 per bird3) and concerning (Salmonellosis represents half of all global foodborne outbreaks requiring hospitalisation4 and causes around 59,000 deaths each year5).


Robust control of Salmonella requires a holistic and integrated approach, with vaccination at its core:

» Excellent biosecurity and hygiene

» Effective vaccination strategy

» Good monitoring and flock management

BOTH is best for superior, direct protection


Co-fermentation diagram



Better protection:

When challenged with a field strain of S.Typhimurium (at much higher levels than would be seen in the field via natural infection), birds vaccinated with AviPro Salmonella Duo had significantly lower numbers of field strains in the caeca and spleen compared with a live S.Enteritidis vaccine1


Reduced shedding into the laying period:

Some live vaccines have shedding patterns that can extend well into the production period, potentially exposing the table egg to vaccine residues9. AviPro vaccines provide the efficacy of live vaccines but are not shed by vaccinated birds during the production period.

Avipro rearing production



Improved egg safety:

Egg claim diagram


Birds vaccinated with AviPro Salmonella Duo demonstrate:

  • Reduced organ contamination, including the reproductive tract6
  • Reduced egg contamination6

Vaccination with AviPro Salmonella Duo reduced egg contamination by 83%


Avipro Salmonella Duo brochure

Avipro Salmonella Duo Detail Aid

Download the Avipro Salmonella Duo detail aid (pdf).

Avipro Early Vaccination Leaflet

Download the Avipro Early Vaccination leaflet (pdf).

Watch our mode of action video to understand more about Salmonella works

  1. Koerich, P. and Doblies, D. Comparison of the efficacy of a live bivalent Salmonella vaccine with a monovalent vaccine against a challenge with a Salmonella Typhimurium field strain. IPPE International Production & Processing EXPO, Altanta (2023).
  2. UK National Control Programme for Salmonella in Layers (gallus gallus): ‘Laying hens and flocks: poultry testing for salmonella’ government guidance. https://www.gov.uk/guidance/ salmonella-get-your-egg-laying-hens-tested 
  3. Elanco Market Research Cost of a Salmonella Outbreak 2023 Free Range 320000 - Scrutton Bland 
  4. EFSA Journal 2021. The European Union One Health 2019 Zoonoses Report. EFSA Journal;19(2):6406 
  5. WHO Estimates of the Global Burden of Foodborne Diseases 2007-2015. https://apps.who.int/iris/bitstream/ handle/10665/199350/9789241565165_eng.pdf. 
  6. Gantois I et al Vaccine 2006 6250 (v1.0)
  7. REF-03435 — Development of a third generation vaccine to prevent Salmonella infections Salmonella infections. 
  8. Barrow, P.A., et al. Faecal shedding and intestinal colonization of Salmonella enterica in in-bred chickens: the effect of host-genetic background. Epidemiology & Infection 132.1 (2004): 117-126. 
  9. Mueller-Doblies D IPPE 2023 2023 1.1 (v1.0) 
  10. SPC Elanco Avipro Salmonella DUO 2016 (v1.0)