Introducing Neptra Ear Drops for Dogs
The only 1-dose treatment for otitis externa with florfenicol
When indicated, florfenical is a 1st-line antibiotic; see the PROTECT ME guidelines*1
Neptra offers a combination of 3 active ingredients that work together against the most common pathogens associated with otitis externa (OE).
- ANTI-INFLAMMATORY
Mometasone furoate
Starts relieving pain and inflammation in just 30 minutes‡2 - ANTIBIOTIC
Florfenicol
When indicated, Florfenicol is a first line antibiotic; see the PROTECT ME guidelines*1 - ANTI-FUNGAL
Terbinafine hydrochloride
Highly effective against M. pachydermatis, a common fungal pathogen associated with otitis externa
Over 70% of canine OE cases are associated with Malassezia pachydermatis or Staphylococcus pseudintermedius3,4. Neptra effectively treats these common pathogens so you can
- Reserve broader spectrum antibiotics for complex cases5
- Avoid "leftover" antibiotics lingering in owners' homes
- Keep OE treatment in safe hands
Neptra delivers lasting efficacy
In a study comparing a single dose of Neptra to once-daily drops administered for 7 days, treatment with Neptra delivered:
- continuous clinical improvement until Day 28
- 87.4% clinical success rate by Day 28

How to Administer Neptra
Administer Neptra to dogs in the following steps:
- Clean
As clinically appropriate for the patient‡‡
- Dry
Wipe or blot away the cleaning solution
- Treat
Use one tube of Neptra per ear and massage the ear base for 30 seconds
Watch how to prepare Neptra and administer the one-dose treatment to dogs:
Treating Otitis Externa
Find out more about treating otitis externa in dogs and the benefits of Neptra one-dose drops. Access this here.
Neptra Resources
We have developed an extensive range of resources, from downloadable assets for you to use in consultations to CPD modules. Access these here.
*for otitis associated with cocci; topical antibiotics may not always be required.1
‡Tmax reached in 30 minutes. Neptra Summary of Product Characteristics 2023.
**otitis associated with Staphylococcus pseudintermedius.3
‡‡In clinical trials, saline was used as the cleaning solution. Ears were cleaned and dried as deemed clinically appropriate for that patient. Compatibility with ear cleaners other than saline has not been demonstrated.
- BSAVA/SAMSoc 'Antibiotic Use in Our Practice' poster 2023.
- Neptra Summary of Product Characteristics 2023.
- Malayeri et al. Identification and antimicrobial susceptibility patterns of bacteria causing otitis externa in dogs. Vet Res Commun (2010) 34, 435-444
- Guillot J et al. Malassezia Yeasts in Veterinary Dermatology: An Updated Overview. Front. Cell. Infect. Microbiol2020;10:79.
- Barnard et al 2017. In Practice 39: 386-398.