REST EASY WITH ONSIOR FOR DOGS

Available as an injectable and tablets, which can be used interchangeably for up to 2 days post surgery

Onsior tablets for dogs (5 mg, 10 mg, 20 mg, 40 mg)

For the treatment of pain and inflammation associated with soft tissue surgery in dogs
For the treatment of pain and inflammation associated with chronic osteoarthritis in dogs

Onsior solution for injection for cats and dogs (20 mg)

For the treatment of pain and inflammation associated with orthopaedic or soft tissue surgery in cats
For the treatment of pain and inflammation associated with orthopaedic or soft tissue surgery in dogs

Wide margin of safety in dogs¹

The safety index of robenacoxib in dogs is thought to be due to its high COX-2 selectivity and short residence time in the central compartment
In safety studies in dogs, no significant adverse events were observed with robenacoxib at doses up to 40 mg/kg

Persists at the site of inflammation while sparing other organs from prolonged drug exposure²

Onsior persists longer and at higher concentrations at the site of inflammation than in the blood, for effective once-daily dosing
Onsior is rapidly eliminated from the blood, sparing well-perfused organs from prolonged drug exposure

Onsior Mode of Action Video

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Dosing chart for Onsior tablets and injection for cats and dogs

King JN, Arnaud JP, Goldenthal EI, et al (2011) Robenacoxib in the dog: target species safety in relation to extent and duration of inhibition of COX-1 and COX-2. J Vet Pharmacol Ther 34(3):298–311.
Silber HE, Burgener C, Letellier IM, et al (2010) Population pharmacokinetic analysis of blood and joint synovial fluid concentrations of robenacoxib from healthy dogs and dogs with osteoarthritis. Pharm Res 27(12):2633–2645.
Previcox® Summary of Product Characteristics.
Metacam® Summary of Product Characteristics.
Rimadyl® Chewable Tablets US package insert.