Hemicell Study Data and Resources
A comprehensive record of studies and resources, as referenced across our Hemicell Pig and Poultry pages.
Hsiao, H., Anderson, D. and Dale, N. 2006. “Levels of β-mannan in Soybean Meal.” Poultry Sci. 85:1430-1432
Song W, et al. (1995) A Receptor Kinase-Like Protein Encoded by the Rice Disease Resistance Gene, Xa21. Science. 270: 1804-1806
Beutler B, et al. (2006) Genetic Analysis of Host Resistance: Toll-Like Receptor Signaling and Immunity at Large. Annu. Rev. Immunol. 24: 353-389
Ausubel F. (2005) Are innate immune signaling pathways in plants and animals conserved? Nature Immunol. 6(10): 973-979
Didierlaurent A, et al. (2005) Innate and acquired plasticity of the intestinal immune system. Cellular and Molecular Life Sciences. 62: 1285-1287
Stahl P, Ezekowitz R. (1998) The mannose receptor is a pattern recognition receptor involved in host defense. Curr. Opin. Immunol. 10(1): 50-55.
Hsiao, H-Y, et al. (2004) “Efficacy of β-mannanase (Hemicell®) in broiler chickens infected with necrotic enteritis." International Poultry Scientific Forum, Abstract 120, The Southern Conference on Avian Diseases
Poulsen, K. Effects of Hemicell on Intestinal Health in broilers analyzed in 44 Experiences. Data on file
Daskiran M, et al. (2004) An Evaluation of Endo-ß-D-mannanase (Hemicell™). Effects on Broiler Performance and Energy Use in Diets Varying in ß-mannan Content.” Poultry Sci. 83: 662-668
Poulsen K, et al. (2023) Meta-analysis on the effect of dietary b-mannanase on intestinal integrity in broiler chickens. J. Appl. Poult. Res. 32:100307
Saeed M, et al. (2019) The Role of ß-Mannanase (Hemicell) in Improving Poultry Productivity, Health and Environment. Brazilian Journal of Poultry Science, v.21, n.3, 001-008.
Elanco trial number ELADE140114. (2014) Analysis of the results of Hemicell-L under commercial conditions in a German broiler integration. Data on file.
Blonk consultants. (2023) A lifecycle assessment (LCA) of both Hemicell production and the comparative performance of feeds containing it
Pettey, L., Carter, S., Senne, B. and Shriver, J. 2002. Effects of s-mannanase addition to corn-soybean meal diets on growth performance, carcass traits, and nutrient digestibility of weanling and growing/finishing pigs. J. Anim. Sci. 80: 1012-1019. REF-00813
Rambo, Z., Ferrel, J., Anderson, D. et al. 2011. “Effect of increasing concentrations of two thermal stable strains of beta-mannanase in corn-soybean meal diets on nursery pig performance.” J. Anim. Sci. 89(E-Suppl.2, abstract 224): 119. REF-01067
Evaluation of Hemicell in Swine Nursery Feeds Using Meta Analysis of Ten Experiments. Elanco Study ENZUS140022 2014. REF-10595
Sánchez-Uribe, et al. 2022. Effect of β-Mannanase Addition during Whole Pigs Fattening on Production Yields and Intestinal Health. Animals 2022, 12, 3012
Genova JL, et al. 2023. β‑mannanase supplemented in diets saved 85 to 100 kcal of metabolizable energy/kg, supporting growth performance and improving nutrient digestibility in grower pigs. Scientific Reports 13:12546
Genova JL, et al. 2023 β-mannanase supplementation in diets reduced in 85 kcal metabolizable energy/kg containing xylanase-phytase improves gain to feed ratio, nutrient usage, and backfat thickness in finisher pigs. Front. Vet. Sci. 10:1144692. doi: 10.3389/fvets.2023.114469
Vangroenweghe, F., Poulsen, K. & Thas, O. Supplementation of a β-mannanase enzyme reduces post-weaning diarrhea and antibiotic use in piglets on an alternative diet with additional soybean meal. Porc Health Manag 7, 8 (2021).
Vangroenweghe, F. & Poulsen, K. 2020. Application of Hemicell HT, a β-mannanase enzyme, restores post-weaned piglet performance in the presence of challenging protein sources. Data on file
Ferrel, J., Anderson, D, and Hsiao, H.-Y. 2014. “Content of Soluble Non-Starch Polysaccharides β-Mannan and Xylan in Legume Meals, Non-Legume Meals, and Cereal Grains or Cereal Grain By-Products.” Journal Animal Science, 92: Abstract #328
Need further help? Speak to our friendly team
Whether you have general queries, product questions, or need support with Elanco Partners, our team is here to help. Reach out via phone or email for fast, direct support.
Hemicell™ XT, Elanco™ and the diagonal bar logo are trademarks of Elanco or its affiliates.
