Beta-mannans are a problem for pig production.
Hemicell™ XT is the solution.
What are beta-mannans?
Naturally occurring feed compounds found in all vegetable-based animal diets1,2
Have a molecular pattern that is similar to some pathogens, prompting an unnecessary immune response (FIIR)3-7
- Diverts energy away from growth
- Reduces gut heath and function
Cannot be broken down naturally in the gut
Resistant to feed processing procedures, such as pelleting and extrusion
The feed-induced immune response (FIIR)3-7:
Access our study data page for more information
1. Hsiao, H., Anderson, D. and Dale, N. 2006. “Levels of β-mannan in Soybean Meal.” Poultry Sci.85:1430- 1432.
2. Ferrel, J., Anderson, D, and Hsiao, H.-Y. 2014. “Content of Soluble Non-Starch Polysaccharides β-Mannan and Xylan in Legume Meals, Non-Legume Meals, and Cereal Grains or Cereal Grain By-Products.” Journal Animal Science, 92: Abstract #328
3. Song W, et al. (1995) A Receptor Kinase-Like Protein Encoded by the Rice Disease Resistance Gene, Xa21. Science. 270: 1804-1806.
4. Beutler B, et al. (2006) Genetic Analysis of Host Resistance: Toll-Like Receptor Signaling and Immunity at Large. Annu. Rev. Immunol. 24: 353-389.
5. Ausubel F. (2005) Are innate immune signaling pathways in plants and animals conserved? Nature Immunol. 6(10): 973-979.
6. Didierlaurent A, et al. (2005) Innate and acquired plasticity of the intestinal immune system. Cellular and Molecular Life Sciences. 62: 1285-1287.
7. Stahl P, Ezekowitz R. (1998) The mannose receptor is a pattern recognition receptor involved in host defense. Curr. Opin. Immunol. 10(1): 50-55.
8. Pettey, L., Carter, S., Senne, B. and Shriver, J. 2002. Effects of s-mannanase addition to corn-soybean meal diets on growth performance, carcass traits, and nutrient digestibility of weanling and growing/finishing pigs. J. Anim. Sci. 80: 1012-1019. REF-00813
9. Rambo, Z., Ferrel, J., Anderson, D. et al. 2011. “Effect of increasing concentrations of two thermal stable strains of beta-mannanase in corn-soybean meal diets on nursery pig performance.” J. Anim. Sci. 89(E-Suppl.2, abstract 224): 119. REF-01067
10. Evaluation of Hemicell in Swine Nursery Feeds Using Meta Analysis of Ten Experiments. Elanco Study ENZUS140022 2014. REF-10595
11. Sánchez-Uribe, et al. 2022. Effect of β-Mannanase Addition during Whole Pigs Fattening on Production Yields and Intestinal Health. Animals 2022, 12, 3012. https://doi.org/10.3390/ani12213012
12. Genova JL, et al. 2023. β‑mannanase supplemented in diets saved 85 to 100 kcal of metabolizable energy/kg, supporting growth performance and improving nutrient digestibility in grower pigs. Scientific Reports 13:12546
13. Genova JL, et al. 2023 β-mannanase supplementation in diets reduced in 85 kcal metabolizable energy/kg containing xylanase-phytase improves gain to feed ratio, nutrient usage, and backfat thickness in finisher pigs. Front. Vet. Sci. 10:1144692. doi: 10.3389/fvets.2023.1144692
