AviPro™ Salmonella Duo in-lay:
Helps protect everyone for longer with the first
dual-strain, in-lay Salmonella vaccine
Why in-lay protection matters
Modern laying cycles can now extend to around 100 weeks.1,2
The later stages of lay are associated with:

Increased Salmonella prevalence3

Prolonged environmental exposure4

Licensed vaccine duration of immunity has, until now, not kept pace with the improvement of longer production cycles
Protection up to 100 weeks
A 4th dose in-lay of AviPro Salmonella Duo at around 50 weeks extends protection:

Up to 100 weeks for Salmonella Enteritidis5,6

Up to 94 weeks for Salmonella Typhimurium5,6
Protection up to 100 weeks

Single 4th dose in-lay (following 3 doses in-rear)5

Simple administration in drinking water5

Zero-day egg withdrawal after 4th dose5,7

Simple differentiation testing


Vaccine strain does
NOT grow on MSRV*8

Growth= field strains
Check your knowledge
Confirm your understanding of the in-lay vaccination application protocol by passing the knowledge check to receive your certificate

After in-lay administration:

Rapid clearance from internal organs7

Lack of faecal shedding7

Absence of egg transmission7

Built on years of trusted global use.
*Modified Semisolid Rappaport-Vassiliadis
1. Bain M, et al. (2016) Increasing persistency in lay and stabilising egg quality in longer laying cycles. What are the challenges? British Poultry Science, 57(3), 330–338. https://doi.org/10.1080/00071668.2016.1161727
2. Turner R. (2020) Salmonella and Considerations for Longer Lay., St Davidʼs Poultry Team. https://www.stdavids-poultryteam.co.uk/news/salmonella-and-considerations-for-longer-lay/ (accessed on 15 October 2020)
3. Elanco data on file. (2025) REF-29014. Shaun Cawthraw, APHA Weybridge, personal communication
4. Samper-Cativiela C, et al. (2023) Risk Factors for Salmonella Detection in Commercial Layer Flocks in Spain. Animals 13(20), 3181; https://doi.org/10.3390/ani13203181
5. AviPro™ Salmonella Duo Summary of Product Characteristics (SPC)
6. Elanco data on file. REF-28459
7. Elanco data on file. REF-28708
8. Desloges N, et al. (2010) Development of a third generation vaccine to prevent Salmonella infections in commercial poultry flocks. Development, 45, 22
PM-UK-26-0130- Self certification questions
