Advantage Multi® for Cats (imidacloprid + moxidectin)

Advantage Multi provides broad-spectrum parasite protection in a convenient monthly topical application, potentially increasing compliance for both indoor and outdoor cats that may not prefer oral medications.

Advantage Multi for Cats Dosing and Administration

One monthly dose protects against 5 types of parasites, including heartworms, roundworms, hookworms, fleas, and ear mites.

Weight (lbs) - 2-5
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Tube Size (mL) -


Weight (lbs) - 5.1-9
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Tube Size (mL) -


Weight (lbs) - 9.1-18*
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*Cats over 18 lbs. should be treated with the appropriate combinations of Advantage Multi for Cats tubes.

How To Apply Advantage Multi for Cats

  • Advantage Multi How to Apply Step 3
    Step 1

    Remove one dose applicator tube from the package. While holding the tube in an upright position, remove the cap from the tube. 

  • Multi How to Apply Step 2
    Step 2

    Turn the cap over and push the other end of the cap onto the tip of the tube. Twist the cap to break the seal, and then remove the cap from the tube. 

  • Multi How to Apply Step 3
    Step 3

    Part the hair on the back of the cat’s neck at the base of the head until the skin is visible

  • Multi How to Apply Step 4
    Step 4

    Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. 

Prescribe Advantage Multi

Advantage Multi provides 5-in-1 protection against fleas, heartworms, roundworms, hookworms and ear mites.

Advantage Multi® (imidacloprid + moxidectin) Resources

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Advantage Multi® for Cats (imidacloprid + moxidectin)


Advantage Multi® for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. Advantage Multi® for Cats kills adult fleas (Ctenocephalides felis) and is indicated for the treatment of flea infestations. Advantage Multi® for Cats is also indicated for the treatment and control of ear mite (Otodectes cynotis) infestations and the following intestinal parasites:


CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). 

Do not use on cats less than 9 weeks of age and cats or ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes following application.