K9 Advantix® II for Dogs

A convenient monthly topical application that kills and repels fleas, ticks and mosquitoes, kills lice and repels biting flies. It’s specifically formulated for dogs with imidacloprid, permethrin, and pyriproxyfen for broad-spectrum protection against these ectoparasites that can transmit diseases to your patients. And because it kills through contact, there’s no biting required. 

K9 Advantix II for Dogs packshot

Why choose K9 Advantix II for your dog or puppy? 

  • Easy-to-apply monthly application.

  • Waterproof after 24 hours.

  • Kills and repels fleas, ticks and mosquitoes through contact, so they don’t have to bite your dog to die.

K9 Advantix II for Dogs Dosing and Administration

For dogs 7 weeks and older.

Dog Weight - 4 – 10 lbs
0.4 mL tube - X
1.0 mL tube - -
2.5 mL tube - -
4.0 mL tube - -
Dog Weight - 11 – 20 lbs
0.4 mL tube - -
1.0 mL tube - X
2.5 mL tube - -
4.0 mL tube - -
Dog Weight - 21 – 55lbs
0.4 mL tube - -
1.0 mL tube - -
2.5 mL tube - X
4.0 mL tube - -
Dog Weight - >55lbs
0.4 mL tube - -
1.0 mL tube - -
2.5 mL tube - -
4.0 mL tube - X

How to Apply K9 Advantix II for Dogs

  • Step 1

    Hold applicator tube in an upright position. Pull cap off tube. 

  • Step 2

    Turn the cap over and push the other end of the cap onto the tip of the tube. Twist the cap to break the seal, and then remove the cap from the tube. 

  • Step 3

    Evenly apply the entire contents of the tube along the top of the dog’s back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of the dog (please refer to the product label). 

  • Step 4

    At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze a portion of the solution on the skin. 

Learn more about K9 Advantix II for Dogs

K9 Advantix II for Dogs is a convenient monthly topical application that kills and repels fleas, ticks , and mosquitoes, kills lice, and repels biting flies. 

Contact your Elanco Representative for more information.

K9 Advantix® II for Dogs

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not contaminate feed or food.


  • Do not allow children to apply product.
  • Do not have contact or allow children to have contact with treated area until completely dry.
  • Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.
  • Do not get this product in your dog’s eyes or allow your dog to ingest this product.
  • Dogs should be dry prior to application and remain dry for 24 hours after application for product to work effectively.
  • Do not use on cats. Keep cats away from treated dogs for 24 hours.

For further information, please refer to the Product Label