First and only monthly chewable tablet to protect against ticks, fleas, heartworm disease, roundworms, hookworms*, and tapeworms

Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) provides the broadestparasite protection available in an isoxazoline endectocide – the first and only of its kind that protects dogs against 6 different types of parasites, including tapeworms.

Lotilaner, one of the active ingredients in Credelio Quattro, has been proven to kill tickstwice as fast§ as sarolaner in Simparica Trio & afoxolaner in NexGard1. Plus, it’s approved for use in dogs and puppies as young as 8 weeks weighing 3.3 pounds or more.

*Uncinaria stenocephala 

Based on label comparison of the number of parasite types covered in an isoxazoline endectocide

Amblyomma americanum (lone star tick)

§Based on the time to statistical significance vs control in a single study on Day 21 and Day 28 for reinfestations. The study compared Credelio® (lotilaner)—not Credelio Quattro™, which contains lotilaner as well as moxidectin, praziquantel, and pyrantel—to the active ingredients in Simparica Trio® (sarolaner, moxidectin, and pyrantel) and NexGard® (afoxolaner).
 

Why Choose Credelio Quattro?

  • First and only monthly chewable to protect against ticks, fleas, heartworm disease, roundworms, hookworms*, and tapeworms. 

  • Heartworm Icon

    In laboratory studies, Credelio Quattro was 100% effective against heartworm disease from the first monthly dose.

  • Stopwatch icon

    Lotilaner in Credelio Quattro kills ticks twice as fast§ as sarolaner in Simparica Trio and afoxalaner in NexGard1.

  • Credelio Logo

    Contains the same established dose of lotilaner used in Credelio.

  • Shield Icon

    Backed by Elanco’s Canine Parasiticides Satisfaction Guarantee.

*Uncinaria stenocephala 

 ‡Amblyomma americanum (lone star tick)

 §Based on the time to statistical significance vs control in a single study on Day 21 and Day 28 for reinfestations. The study compared Credelio® (lotilaner)—not Credelio Quattro™, which contains lotilaner as well as moxidectin, praziquantel, and pyrantel—to the active ingredients in Simparica Trio® (sarolaner, moxidectin, and pyrantel) and NexGard® (afoxolaner).

Credelio Quattro Dosing and Administration

  • Checkmark

    A tasty beef-flavored meat-allergen-free chewable crafted for sensitive dogs2

  • Checkmark

    Once monthly administration with food or within 30 minutes of a meal

  • Checkmark

    Year-round protection for dogs and puppies 8 weeks of age and older and 3.3 pounds or greater

Credelio Quattro is available in 5 different weight bands making it suitable for dogs weighing 3.3 lbs. and above.

Not actual size.

Resources

2024 Speed of Tick Kill Technical Bulletin

Frequently Asked Questions

Indications for Credelio Quattro

Credelio Quattro is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina), hookworm (adult Unicaria stenocelphala), and tapeworm (Dipylidium caninum, Taenia pisiformis, and Echinococcus granulosus) infections.
Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick) and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.

Important Safety Information for Credelio Quattro

Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. For full prescribing information see Credelio Quattro package insert.

About Elanco

Learn why we're a leading provider of innovative solutions that protect and enhance animal health.

Connect with Elanco

Credelio Quattro, Credelio, Elanco and diagonal bar logo are trademarks of Elanco or its affiliates. All other company and product names are trademarks of their respective owners. PM-US-24-1123

© 2024 Elanco or its affiliates.