Kill ticks* faster with Credelio® (lotilaner)

Credelio is a small, tasty1 beef flavored chewable made with an extra purification process, keeping only what's needed - lotilaner - and removing the rest. So, it's gentle on dogs but not on ticks and fleas. In fact, Credelio kills ticks* faster than Simparica Trio® (sarolaner, moxidectin, pyrantel) and NexGard® (afoxolaner)1.


*A. americanum (lone star tick)

Extra purified, gentler on dogs, easier on digestive system   

An extra purification step is taken for the active ingredient mixture, leaving only the active portion of lotilaner in the final product. 

BENEFITS OF EXTRA-PURIFICATION INCLUDE: 

  • Less potential for side effects

    Less potential for side effects5

  • More efficient drug delivery in a small tablet that is easy to give

    More efficient drug delivery in a small tablet that is easy to give2

  • Less work for the dog or puppy's body to process

    Less work for the dog or puppy's body to process2

Mode of Action Video

Credelio – Made for ease, efficacy, and speed  

  • Fast: Credelio kills ticks faster than Simparica Trio & Nexgard
    Fast

    Credelio kills ticks* faster than Simparica Trio & Nexgard1 

    *Amblyomma americanum (lone star tick) 

  • Purified: Our active ingredient extra-purification process means your dog gets only what it needs in the final product formulation.
    Purified

    Our active ingredient extra-purification process means your dog gets only what it needs in the final product formulation.

  • Gentle: Credelio is gentle enough for dogs and puppies as small as 4.4 lbs or greater and as young as 8 weeks of age.
    Gentle

    Credelio is gentle enough for dogs and puppies as small as 4.4 lbs or greater and as young as 8 weeks of age.

Effective against Fleas  

In a controlled laboratory study, Credelio killed fleas before they could lay eggs, preventing further infestations for 30 days.

By killing biting fleas quickly, Credelio can help relieve flea allergy dermatitis (FAD).9,10 

After only one dose, Credelio reduced pruritus and skin lesions with no need for steroids thanks to its fast flea kill.10

Credelio Dosing Table

Credelio is available in 5 different weight classes, enabling you to offer pet owners convenient and easy administration for dogs 4.4 lbs and up.

Administering Credelio

For full efficacy against ticks and fleas, instruct pet owners to always give their dog Credelio with food or within 30 minutes of a meal. The presence of food ensures that peak blood levels and exposures are achieved, which is necessary for initial and ongoing efficacy.

Credelio should be administered once a month, every month, to dogs and puppies 8 weeks of age and older and 4.4 pounds or greater to provide year-round protection.

Credelio® (lotilaner) Resources

2024 Speed of Tick Kill Technical Bulletin

Credelio® (lotilaner) for Dogs

Indications 

Credelio® (lotilaner) kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick) and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs and puppies 8 weeks of age and older and weighing 4.4 pounds or greater.  

Important Safety Information (ISI)

Lotilaner is a member of the isoxazoline class.  This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving this class of drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. The safe use of Credelio® in breeding, pregnant or lactating dogs has not been evaluated. The most frequently reported adverse reactions are weight loss, elevated blood urea nitrogen, polyuria, and diarrhea.  For full prescribing information see the Credelio® package insert.

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