Trifexis® (spinosad + milbemycin oxime)
Trifexis is a monthly, beef-flavored tablet that kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm, roundworm and whipworm infections. Intended for use in dogs and puppies 8 weeks and older who weigh 5 lbs or more.
Protect with Trifexis
Kills fleas and prevents infestations
Prevents heartworm disease
Treats and controls adult hookworm, roundworm, whipworm; prevents heartworm disease; prevents and treats flea infestations
Why prescribe Trifexis?
Protect against fleas, heartworm disease and hookworms, roundworms and whipworms
Starts killing fleas in just 30 minutes
Easy-to-administer, monthly beef-flavored chewable tablet
Available in 5 varying doses for dogs and puppies ranging from 5 – 120 lbs.
Trifexis Dosing and Administration
| Product name - Trifexis (Magenta Box) |
| Weight bands - 5 – 10 lbs |
| Product name - Trifexis (Orange Box) |
| Weight bands - 10.1 – 20 lbs |
| Product name - Trifexis (Green Box) |
| Weight bands - 20.1 – 40 lbs |
| Product name - Trifexis (Blue Box) |
| Weight bands - 40.1 – 60 lbs |
| Product name - Trifexis (Brown Box) |
| Weight bands - 60.1 – 120 lbs |
| Product name - Administer the appropriate combination of tablets |
| Weight bands - > 120 lbs |
| Product name | Weight bands |
|---|---|
| Trifexis (Magenta Box) | 5 – 10 lbs |
| Trifexis (Orange Box) | 10.1 – 20 lbs |
| Trifexis (Green Box) | 20.1 – 40 lbs |
| Trifexis (Blue Box) | 40.1 – 60 lbs |
| Trifexis (Brown Box) | 60.1 – 120 lbs |
| Administer the appropriate combination of tablets | > 120 lbs |
Trifexis® (spinosad + milbemycin oxime) Resources
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Stock Trifexis at your clinic
Trifexis offers your patients 3-in-1 protection against fleas, heartworm disease, and intestinal parasites, including hookworm, roundworm and whipworm.
Trifexis® (spinosad + milbemycin oxime)
Indications
Trifexis® is indicated for the prevention of heartworm disease (Dirofilaria immitis). Trifexis® kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), and the treatment and control of adult hookworm (Ancylostoma caninum), adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.
Important Safety Information (ISI)
Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis®. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis®, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis® in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. The most common adverse reactions reported are vomiting, depression/lethargy, pruritus, anorexia, and diarrhea. To ensure heartworm prevention, dogs should be observed for one hour after administration. If vomiting occurs within one hour of administration, redose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. For full prescribing information see Trifexis® package insert.