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Interceptor® Plus (milbemycin oxime/praziquantel)

Interceptor Plus is a once-monthly flavored chew that protects against all 5 major types of dangerous worms in dogs.

Why choose Interceptor Plus?

  • Worm Icon
    Interceptor Plus is indicated for the treatment of 5 different types of worms, protecting dogs and puppies against heartworm disease, adult hookworm, roundworm, tapeworm and whipworm infections.


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    Single monthly chew for easy administration.


  • Dose Icon
    Interceptor Plus comes in 4 convenient dosing sizes.


Interceptor Plus Dosing and Administration

Product - Milbemycin Oxime (per tablet)
2-8 lbs -

2.3 mg

8.1-25 lbs -

5.75 mg

25.1 - 50 lbs -

11.5 mg

50.1 - 100 lbs -

23 mg

100+ lbs -

Administer the appropriate combination of chewable tablets.

Product - Praziquantel (per tablet)
2-8 lbs -

22.8 mg

8.1-25 lbs -

57 mg

25.1 - 50 lbs -

114 mg

50.1 - 100 lbs -

228 mg

100+ lbs -

Administer the appropriate combination of chewable tablets.

How To Administer Interceptor Plus

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    1. Remove 1 Tasty Chewable from its Packaging

    Check to make sure that the chewable has not expired and remove from packaging.

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    2. Administer Chewable

    The dog can take the chewable from the hand or with a small amount of food. Make sure it consumes the whole dose.

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    3. Check for Complete Ingestion

    After the dog has taken the chewable, observe it for a few minutes to ensure that no part of the dose is lost or rejected. If you suspect that any of the dose has been lost, redosing is recommended.

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Don’t Leave a Gap in Their Coverage

Interceptor Plus is a once-monthly flavored chew that protects against all 5 major types of dangerous worms in dogs: heartworm, hookworm, roundworm, whipworm and tapeworm.

Interceptor® Plus (milbemycin oxime/praziquantel) Resources

Canine Parasiticides Satisfaction Guarantee

Indications for Interceptor® Plus

Interceptor® Plus is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Taenia pisiformis, Echinococcus multilocularis, Echinococcus granulosus and Dipylidium caninum) infections in dogs and puppies 6 weeks or older and 2 pounds or greater.

Important Safety Information

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor® Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor® Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, depression/lethargy, ataxia, anorexia, convulsions, weakness, and salivation. For full prescribing information see the Interceptor® Plus package insert.

Indications for Credelio® (lotilaner)

Credelio® (lotilaner) kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick) and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs and puppies 8 weeks of age and older and weighing 4.4 pounds or greater.  

Important Safety Information (ISI)

Lotilaner is a member of the isoxazoline class.  This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving this class of drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. The safe use of Credelio® in breeding, pregnant or lactating dogs has not been evaluated. The most frequently reported adverse reactions are weight loss, elevated blood urea nitrogen, polyuria, and diarrhea.  For full prescribing information see the Credelio® package insert.

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Interceptor, Credelio, 360 Protection, Elanco and diagonal bar logo are trademarks of Elanco or its affiliates. PM-US-22-1240

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