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Onsior® (robenacoxib) for Cats

The No.1 prescribed feline NSAID1

Why Choose Onsior?

  • Convenient to administer. Injectable form or pill form for vets to administer in clinic, and pill form for pet owners to administer at home.

  • Rapid Relief
    A coxib NSAID that is rapidly absorbed, persists at the site of inflammation and is rapidly cleared from the bloodstream.*2

    Effective at controlling the postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy, and castration in cats.

    *Clinical relevance unknown.

  • Well-tolerated when administered. 
    For injection, it has demonstrated efficacy for cats for use up to a maximum of 3 days. For tablets at a dose of 1 mg/kg (tablets) once daily or at a dose of 2 mg/kg subcutaneously once daily to cats for up to a maximum of 3 days.

Onsior Dosing Table

Feline Tablet Dosing Range

6 mg Tablets - 1
Weight (lbs) -

5.5 to 13.2 lbs

Weight (kg) -

2.5 to 6 kg

6 mg Tablets - 2
Weight (lbs) -

13.3 to 26.4 lbs

Weight (kg) -

6.1 to 12 kg

Subcutaneous Injection Dosing

Dose in Kilograms - 2 mg/kg
Dose in pounds -

0.91/lb

Administering Onsior for Surgery

DAY 1 - Administer the first Onsior dose approximately 30 minutes before soft-tissue surgery.
DAY 2 -

Administer (or instruct the owner to administer) the second Onsior dose approximately 24 hours after the first dose.

DAY 3 -

Administer (or instruct the owner to administer) the third and last Onsior dose approximately 24 hours after the second dose.

How does Onsior work?

  • Onsior is quickly absorbed. Peak blood concentrations are attained rapidly with median Tmax values generally occurring within 0.5 hr.*

  • Onsior, a highly protein-bound NSAID, persists longer at the site of inflammation than in the blood because inflammatory exudate is rich in plasma proteins, thereby providing sustained drug levels at the site of action.*2

  • Onsior is rapidly eliminated from the blood. The mean blood T1/2 is approximately 1.7 hrs for Onsior Tablets for Cats.* The terminal T1/2 is approximately 1.1 hrs. for Onsior injection for Cats.***


* Tablets dosed at 1 mg/kg without food.

**Clinical relevance unknown.

*** Injection dosed at 2 mg/kg.

Onsior® (robenacoxib) Resources

Help get them from the hospital to home comfortably

To discover how you can incorporate Onsior into your surgical protocol today, contact your local Elanco rep, distributor rep or call Elanco at 1-888-545-5973.

Onsior® (robenacoxib) for Cats

Indications for Cats

ONSIOR® tablets for Cats are indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration, in cats ≥ 5.5 lbs and ≥ 4 months of age; for up to a maximum of 3 days.

ONSIOR® injection is indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration in cats ≥ 4 months of age; for up to a maximum of 3 days.


Important Safety Information for Cats

ONSIOR® injection: For subcutaneous use in cats ≥ 4 months of age. Safety has not been demonstrated for intravenous or intramuscular administration. The most common adverse reactions were incision site infection, increased incision site bleeding, vomiting, inappetence and lethargy. For full prescribing information, please see package insert.


ONSIOR® tablets for Cats: For oral use in cats ≥ 5.5 lbs and ≥ 4 months of age only. The most common adverse events are anorexia, depression, vomiting, elevated BUN, elevated creatinine, and renal insufficiency/failure. For full prescribing information, please see package insert.

Injectable Package Insert

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