You've trusted Trifexis to protect your patients from heartworm disease, fleas and intestinal parasites.

  • Kills fleas on dogs and prevents infestations


  • Prevents heartworm disease in dogs


  • Treats and controls hookworm, roundworm and whipworm infections


Only pay for what they need

Question: Are ticks a concern for your patients or a problem in your area? If you answered "NO," offer Trifexis, the affordable, monthly, all-in-one beef-flavored tablet that provides comprehensive coverage against multiple parasites without overprotecting against those that don't pose a threat, such as ticks!

Stock Trifexis at your clinic.

Contact your Elanco representative to place an order.

Indications

Trifexis® is indicated for the prevention of heartworm disease (Dirofilaria immitis). Trifexis® kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), and the treatment and control of adult hookworm (Ancylostoma caninum), adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.

Important Safety Information (ISI)

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis®. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis®, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis® in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. The most common adverse reactions reported are vomiting, depression/lethargy, pruritus, anorexia, and diarrhea. To ensure heartworm prevention, dogs should be observed for one hour after administration. If vomiting occurs within one hour of administration, redose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. For full prescribing information see Trifexis® package insert.