Make More Dogs Quattro Dogs with 7 in 1 Coverage
Credelio Quattro™/Credelio Quattro-CA1 is the broadest* parasite coverage available in an isoxazoline endectocide. Unlike other isoxazoline endectocides, Credelio Quattro/Credelio Quattro-CA1 covers 7 types of parasites^ in one flavored chewable tablet.
*Based on label comparison of the number of parasite types covered in an isoxazoline endectocide for dogs
^Credelio Quattro protects dogs against ticks, fleas, heartworm disease, roundworms, hookworms and tapeworms. Credelio Quattro-CA1 is conditionally approved for the treatment of New World screwworm larvae infestations in dogs pending a full demonstration of effectiveness.
Why choose Credelio Quattro/Credelio Quattro-CA1?
100% effective at preventing heartworm disease from the first dose*
*In laboratory studies
Credelio Quattro is proven to kill ticks§ faster¶ than Simparica Trio® and NexGard® Plus 1
Contains the same established dose of lotilaner found in Credelio®
The first and only canine oral isoxazoline endectocide that treats and controls 3 species of tapeworms‡
The broadest parasite coverage of its kind*, targeting 7 types of parasites✝, including ticks, fleas, heartworm disease, roundworms, hookworms, tapeworms, and New World screwworm.
*Based on label comparison of the number of parasite types covered in an isoxazoline endectocide for dogs.
§Ixodes scapularis (black-legged tick)
¶Based on the time to statistical significance vs. control at all 8-, 12- and 24-hour evaluation time points in a head-to-head study on Day 0 post-treatment and on Day 28 for reinfestation. The study compared Credelio Quattro, which contains lotilaner as well as moxidectin, praziquantel, and pyrantel—to the active ingredients in Simparica Trio (sarolaner, moxidectin, and pyrantel) and NexGard Plus (afoxolaner, moxidectin, and pyrantel) against Ixodes scapularis.
✝Credelio Quattro protects dogs against ticks, fleas, heartworm disease, roundworms, hookworms and tapeworms. Credelio Quattro-CA1 is conditionally approved for the treatment of New World screwworm larvae infestations in dogs pending a full demonstration of effectiveness
‡Dipylidium caninum, Taenia pisiformis and Echinococcus granulosus.
Successfully administered to 98% of dogs in a U.S. field study4
Trusted Protection:
Credelio Quattro Protection Against Ticks and Fleas
In a study, lotilaner was shown to inhibit the neuromuscular function of ticks§ in just 2 hours.2
In households with existing flea infestations of varying severity, just 3 monthly doses of lotilaner reduced flea populations by 99.5-100%.
§Amblyomma americanum (lone star tick)
When it comes to killing fleas and ticks, you want it done fast
- 4 HOURS Starts killing fleas in just 4 hours
- 8 HOURS Kills >99% of fleas within just 8 hours of administration3
- 12 HOURS Lotilaner kills 100% of fleas within 12 hours and remains effective for an entire month3
Half-Life
Lotilaner reaches peak absorption in only 2 hours and maintains high, sustained blood levels for the entire month.8
Easy to Pick Up, Hard to Diagnose
Tapeworm infections are common, but some can be easy to miss.
Dipylidium caninum can be diagnosed by their shedding of large, visible proglottids. Adult tapeworms range from 15-70 cm.9
Echinococcus are difficult to diagnose due to their small size and low number of body segments. E. granulosus grow to just 2-7 mm.10
A Disease Risk
Tapeworms don't just threaten dogs: they can be passed to humans. CAPC recommends monthly deworming of dogs with praziquantel in areas where E. granulosus tapeworms are endemic.10
A single monthly dose of Credelio Quattro has been shown to be 100% efficacious against tapeworms# in dogs with its industry-established dose of praziquantel (2.28mg/lb).
#Echinococcus granulosus, Dipylidium canium, and Taenia pisiformis
Want to Learn More?
Take a deep dive into the broadest parasite coverage of its kind* targeting 7 types of parasites☨ - all in one chewable tablet.
*Based on label comparison of the number of parasite types covered in an isoxazoline endectocide for dogs
☨Credelio Quattro protects dogs against ticks, fleas, heartworm disease, roundworms, hookworms and tapeworms. Credelio Quattro-CA1 is conditionally approved for the treatment of New World screwworm larvae infestations in dogs pending a full demonstration of effectiveness.
Indications: Credelio Quattro is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina), hookworm (fourth stage larvae, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala), and tapeworm (Dipylidium caninum, Taenia pisiformis, and Echinococcus granulosus) infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (longhorned tick)] for one month in dogs and puppies 8 weeks of age and older, and weighing 3.3 pounds or greater. Credelio Quattro is indicated for the prevention of Borrelia burgdorferi infections (also known as Lyme disease) as a direct result of killing Ixodes scapularis vector ticks.
Credelio Quattro-CA1 is conditionally approved for the treatment of infestations caused by New World screwworm (NWS; Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.
Important Safety Information: Lotilaner, an ingredient in Credelio Quattro/Credelio Quattro-CA1, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro/Credelio Quattro-CA1 administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea.
Credelio Quattro-CA1 is conditionally approved by the FDA pending a full demonstration of effectiveness under application number 141-619. Treatment of NWS myiasis includes removal of the larvae, lesion cleaning and surgical debridement. Implement appropriate wound care and pain management.
For full prescribing information, see the Credelio Quattro/Credelio Quattro-CA1 package insert.
Credelio
Indications: Credelio kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick) Rhipicephalus sanguineus (brown dog tick) and Haemaphysalis longicornis (longhorned tick)] for one month in dogs and puppies 8 weeks of age and older and weighing 4.4 pounds or greater. Credelio is indicated for the prevention of Borrelia burgdorferi infections (also known as Lyme disease) as a direct result of killing Ixodes scapularis vector ticks.
Important Safety Information: Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving this class of drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. The safe use of Credelio in breeding, pregnant or lactating dogs has not been evaluated. The most frequently reported adverse reactions are weight loss, elevated blood urea nitrogen, polyuria, and diarrhea. For full prescribing information see Credelio package insert.
